Promotor: Prof. dr. J. Boonstra

1. General introduction

• 2. An introduction to actin
  

  2.1 Signal transduction and actin in the regulation of G1-phase progression
  2.2 Appendix

• 3. Attachment of HeLa cells during early G1 phase
  
• 4. Co-localization of the PDGF ß-receptor and actin during PDGF stimulation in mouse fibroblasts
  
• 5. Novel role of cPLA2a in membrane and actin dynamics
  
• 6. Actin dynamics in microgravity
  

6.1 Actin in simulated microgravity
Simulation of microgravity by magnetic levitation and random positioning: effect on human A431 cell morphology
6.2 Actin in real microgravity
Actin dynamics in mouse fibroblasts in microgravity:
a. Dutch Soyuz Mission
b. MASER-10 Mission

• 7. Summarizing discussion
  
• Summary
  
• Samenvatting
  
• Illustrations
  
• Dankwoord
  
• List of publications
  
• Curriculum vitae